全文获取类型
收费全文 | 5096篇 |
免费 | 403篇 |
国内免费 | 223篇 |
专业分类
耳鼻咽喉 | 34篇 |
儿科学 | 20篇 |
妇产科学 | 26篇 |
基础医学 | 689篇 |
口腔科学 | 816篇 |
临床医学 | 315篇 |
内科学 | 410篇 |
皮肤病学 | 62篇 |
神经病学 | 108篇 |
特种医学 | 189篇 |
外国民族医学 | 1篇 |
外科学 | 419篇 |
综合类 | 743篇 |
一般理论 | 3篇 |
预防医学 | 489篇 |
眼科学 | 89篇 |
药学 | 636篇 |
中国医学 | 612篇 |
肿瘤学 | 61篇 |
出版年
2024年 | 12篇 |
2023年 | 93篇 |
2022年 | 129篇 |
2021年 | 373篇 |
2020年 | 195篇 |
2019年 | 138篇 |
2018年 | 163篇 |
2017年 | 157篇 |
2016年 | 163篇 |
2015年 | 209篇 |
2014年 | 388篇 |
2013年 | 426篇 |
2012年 | 304篇 |
2011年 | 351篇 |
2010年 | 258篇 |
2009年 | 248篇 |
2008年 | 267篇 |
2007年 | 242篇 |
2006年 | 209篇 |
2005年 | 195篇 |
2004年 | 160篇 |
2003年 | 152篇 |
2002年 | 123篇 |
2001年 | 100篇 |
2000年 | 73篇 |
1999年 | 57篇 |
1998年 | 67篇 |
1997年 | 63篇 |
1996年 | 43篇 |
1995年 | 42篇 |
1994年 | 31篇 |
1993年 | 23篇 |
1992年 | 31篇 |
1991年 | 30篇 |
1990年 | 22篇 |
1989年 | 15篇 |
1988年 | 17篇 |
1987年 | 9篇 |
1986年 | 13篇 |
1985年 | 22篇 |
1984年 | 24篇 |
1983年 | 22篇 |
1982年 | 13篇 |
1981年 | 8篇 |
1980年 | 14篇 |
1979年 | 4篇 |
1978年 | 6篇 |
1976年 | 7篇 |
1972年 | 3篇 |
1970年 | 2篇 |
排序方式: 共有5722条查询结果,搜索用时 15 毫秒
51.
AIM: To record the cytotoxicity of Resilon and Epiphany (Pentron clinical technologies, Wallingford, CT, USA) using a root model. METHODOLOGY: Thirty teeth with single roots were sectioned at the enamel-cementum junction, the root canals prepared and each root then sterilized before filling with the lateral condensation technique using one of three filling materials (n = 10 per group): Resilon and Epiphany, Sealite (Septodont, Pierre Rolland, Merignac, France) and gutta-percha, Roekoseal Automix (Coltène/Whaledent, Langenau, Germany) and gutta-percha. The roots were stored at 37 degrees C in an incubator to allow for setting of the root filling materials. The apices of the roots were dipped in 1 mL of MEM culture medium for 1, 2, 7 and 30 days renewing the medium every day. After 24 h contact between the medium and the filled roots, the medium was used to measure the cytotoxicity on mouse fibroblasts L 929 with the MTT assay that recorded the mitochondrial activity of the target cells. An additional test according to ISO 10993-5 standards was undertaken to compare Resilon and Epiphany. RESULTS: The root model showed no statistically significant differences between the sealers at 7 and 30 days (NS). Epiphany and Resilon were the most cytotoxic materials at 1 and 2 days (P < 0.001). Unlike Epiphany, Resilon was not cytotoxic when tested according to ISO 10993-5 standards. CONCLUSIONS: The cytotoxicity of Resilon + Epiphany, due mainly to Epiphany, decreased after 2 days to reach a level comparable with commonly used root canal sealers. 相似文献
52.
IPS-Empress全瓷冠临床观察 总被引:10,自引:0,他引:10
目的 :探讨IPS -Empress可铸玻璃陶瓷的修复效果 ,为临床应用提供参考。 方法 :对 68例 179个全瓷冠修复 3年观察 ,对前牙和后牙全瓷冠单冠修复的临床效果进行评价。结果 :68例 79个修复体具有良好的边缘密合性 ,色泽稳定 ,强度高 ,成功率达 86.0 8%。前牙成功率 97.68% ,后牙成功率 70 .0 0 %。结论 :IPS -Empress是一种修复效果较好的全瓷修复材料 相似文献
53.
Cynthia S. Petrie DDS MS ; Mary P. Walker DDS PhD ; Karen Williams PhD 《Journal of prosthodontics》2005,14(4):253-262
PURPOSE: The purpose of this study was to survey members of The American College of Prosthodontists (ACP) to evaluate current materials and methods for final impressions for complete denture prosthodontics in the United States. In addition, those methods were compared with methods and materials taught in U.S. dental schools via a second survey sent to the chairpersons of prosthodontic/restorative departments. MATERIALS AND METHODS: An anonymous questionnaire was mailed to all 1762 active ACP members in the United States in 2003. A slightly modified questionnaire was also distributed to chairpersons of prosthodontic/restorative departments in the 54 U.S. dental schools. Data analysis was performed via frequency distribution and chi-square statistics. RESULTS: Nine hundred and forty-five questionnaires were returned by members of the ACP (54% return rate) and 42 questionnaires were returned by the U.S. dental schools (78% return rate). The majority of the reporting prosthodontists (88%) and dental schools (98%) use a border-molded custom tray for final impressions for complete denture prosthodontics. The most popular material for border molding was plastic modeling compound (67% of reporting ACP members, and 95% of the responding dental schools). Variability of the materials used for final impressions was observed, with the most popular materials being polyvinylsiloxane for the ACP members (36%) and polysulfide for the dental schools (64%). Statistically significant differences were found in the materials used for border molding by prosthodontists based on the time elapsed since completion of prosthodontic training. No differences were found in the materials used for impression of edentulous arches based on years of experience. Geographic location did not influence the materials and methods used by prosthodontists for complete denture final impressions. CONCLUSIONS: There was variability of the materials and techniques used for final impressions by ACP members and dental schools; however, overall there was an agreement on the materials and techniques used by prosthodontists and dental schools. Distinct trends for increasing use of polyvinylsiloxane and polyether for border molding procedures and impressions of edentulous arches were observed both in members of the ACP and in the U.S. dental schools. 相似文献
54.
55.
Influence of core material on fracture resistance and marginal adaptation of restored root filled teeth 总被引:1,自引:0,他引:1
Aim To investigate ex vivo the influence of direct placement core materials on the fracture strength and marginal adaptation of root filled maxillary central incisors restored with glass fibre‐reinforced posts, various core materials and all‐ceramic crowns. Methodology Forty‐eight human maxillary incisors were root filled. Posts were placed and teeth restored with composite cores and crowns (n = 8). Six core materials were examined after thermal cyclic and mechanical loading (TCML). Fracture force was determined under static loading. The marginal adaptation at the interfaces between cement‐tooth and cement‐crown were categorized as ‘intact margin’ or ‘marginal gap’ using scanning electron microscopy. Statistical analysis was undertaken with the Mann–Whitney U‐test (α = P ≤ 0.05). Results Median fracture strength varied between 204 N (low viscous experimental core) and 1094 N (Multicore). No difference in fracture resistance was found with varying viscosity of the core material. The layering technique improved the fracture performance (P = 0.059) to a minor degree. Crowns with dedicated core materials (Rebilda 1063 N; Multicore 1094 N) had a significantly higher fracture resistance than crowns with a conventional restorative material (Tetric Ceram 509 N). Significantly poorer marginal adaptation before TCML was found for the layering technique at the tooth–cement interface and for all experimental cores after TCML. At the crown–cement interface significant differences in marginal adaptation could be determined between Multicore‐layered core (P = 0.002) and Multicore‐Rebilda (P = 0.001) after TCML. Conclusions The fracture strength of post and core restorations was dependent on the core material and bonding system. Marginal adaptation was influenced by the method of application of the core material and by TCML. 相似文献
56.
矿物三氧化物凝聚体用于犬牙直接盖髓的实验研究 总被引:4,自引:0,他引:4
目的:观察矿物三氧化物凝聚体(MTA)直接盖髓后牙髓炎症反应和修复性牙本质的形成。方法:人工机械暴露犬牙髓,用MTA或氢氧化钙直接盖髓。结果:实验2周和8周,MTA诱导修复性牙本质形成的效果优于氢氧化钙,炎症反应较轻。结论:MTA是一种效果较好的盖髓剂。 相似文献
57.
Murata H Kawamura M Hamada T Chimori H Nikawa H 《Journal of oral rehabilitation》2004,31(11):1115-1122
This study examined physical properties and compatibility with dental stones of two types of alginate impression materials. Five powder-type alginate impression materials (Alginoplast EM, Aroma Fine, Algiace Z, Coe Alginate, Jeltrate Plus) and a paste-type alginate impression material (Tokuso AP-1) were used. The dynamic viscosity immediately after mixing was measured by means of a controlled-stress rheometer. The gelation times were determined according to Japanese Industrial Standards (JIS) T6505, and recovery from deformation, strain in compression and compressive strength were determined according to the International Organization for Standardization (ISO) specification 1563. Detail reproduction and surface roughness of type III dental stones (New Plastone, New Sunstone) and a type IV dental stone (Die Stone) were evaluated using a ruled test block as specified in the ISO specification 1563 and a profilometer, respectively. The alginate impression materials evaluated in this study were all in compliance with the ISO specification 1563 and JIS T6505. The alginate impression materials had similar mechanical properties after gelation, whilst a wide range of dynamic viscosity immediately after being mixed, gelation times and compatibility with dental stones were found among the materials. The paste-type material had a higher dynamic viscosity and a shorter gelation time than the powder-type materials. The best surface quality was obtained with the paste-type material/type III dental stone cast combinations. The materials should be selected in consideration of initial flow, setting characteristics and compatibility with dental stones. The results suggested that a paste-type material would better meet the requirements of an alginate impression material. 相似文献
58.
本文阐述了牙槽突裂植入骨的来源,认为自体骨如髂骨仍是最佳材料。有研究应用重组人骨形成蛋白、小牛骨粉及生物胶原膜、组织工程成骨材料修复牙槽突裂取得一定效果。术前适当的正畸治疗对于部分牙槽突裂患者相当重要,术后正畸也必不可少。影响牙槽突裂移植骨成活率的原因较多,包括适应证的选择、手术时机及手术技巧等。应用三维CT评价牙槽突裂植骨较以往的牙片可以获得更全面的信息。 相似文献
59.
OBJECTIVES: The purpose of this study was to examine the influence of variability in bone properties and loading on peri-implant crestal and cancellous bone strains using a probabilistic approach, in combination with finite element (FE) analysis. MATERIAL AND METHODS: Oblique occlusal loading was applied to a single endosseous implant embedded in a two-dimensional (2-D) FE model of a premolar section of a mandible. Perfect bonding was assumed at all interfaces. Five independent parameters (cortical bone thickness (T), cortical (ECORT) and cancellous (ECANC) bone Young's moduli, and vertical (FVERT) and horizontal (FHOR) occlusal forces) were assigned statistical distributions based on data in the literature. Two cancellous bone distribution models were examined, one with a lower mean and range (LM) and the second with a higher mean and range (HM) of cancellous bone Young's modulus values. Sets of randomly chosen values for the five parameters were selected from the distributions and FE analyses were performed for all randomly selected sets. RESULTS: In the LM model, 50% of the cases experienced hyper-physiologic peri-implant crestal strains in the region of commonly reported saucerization, compared with about 25% of the cases in the HM model. Relative probabilistic sensitivities (%) of bone strains to the independent input parameters (T, ECORT, ECANC, FVERT and FHOR) were as follows: 29, 11, 30, 13, and 17 for the LM model, and 17, 11, 35, 21, and 15 for the HM model, respectively. CONCLUSION: Probabilistic analyses of FE models suggest that up to twice as many cases in the LM distribution may be at risk of saucerization as compared with the HM distribution model. Although based on hypothetical distribution values and the limitations inherent to a 2-D analysis, this probabilistic study demonstrated that FE models are very sensitive to the often arbitrarily assigned values for cancellous bone Young's modulus, and also to values used for cortical bone thickness, when the cancellous bone modulus is low. 相似文献
60.
本文报道用Ames法检测了1种新型义齿软衬材料的致突变性,结果表明,经TA97、TA98、TA100和TA102株测试的材料在平皿掺入试验中未诱发阳性反应,但是4个菌株所对应的突变剂均诱发了阳性突变,因此所测试的义齿软衬材料在本实验条件下无诱发突变作用。 相似文献